Therapeutic strategies for synchronous and multiple liver metastases from colorectal cancer

Metastasis in the liver is one of the most critical factors in the prognosis of patients with colorectal cancer. The incidence of synchronous liver metastasis has been found to be approximately 20-25%, but the optimal timing of surgical resection remains controversial. Neoadjuvant chemotherapy has a...

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Bibliographic Details
Main Authors: Shinji Osada, Hisashi Imai, Yoshiyuki Sasaki, Yoshihiro Tanaka, Nobuhisa Matsuhashi, Naoki Okumura, Michitaka Nagase, Kenichi Nonaka, Kazuhiro Yoshida
Format: Article
Language:English
Published: PAGEPress Publications 2012-06-01
Series:Oncology Reviews
Subjects:
Online Access:http://www.oncologyreviews.org/index.php/or/article/view/189
Description
Summary:Metastasis in the liver is one of the most critical factors in the prognosis of patients with colorectal cancer. The incidence of synchronous liver metastasis has been found to be approximately 20-25%, but the optimal timing of surgical resection remains controversial. Neoadjuvant chemotherapy has also been found to be beneficial not only for initially unresectable but also resectable synchronous metastases and traditional surgical strategies of hepatic resection with past chemotherapeutic regimens have been used less and less over the past several years. This review will discuss treatments in association with the recently developed chemotherapeutic regimens.
ISSN:1970-5557
1970-5565