Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Abstract E74-like ETS transcription factor 5 (ELF5) is involved in a wide spectrum of biological processes, e.g., mammogenesis and tumor progression. We have identified a list of p300-interacting proteins in human breast cancer cells. Among these, ELF5 was found to interact with p300 via acetylation...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-021-00158-3 |