Pharmacogenetics and Age-Related Macular Degeneration

Pharmacogenetics and Age-Related Macular Degeneration

Pharmacogenetics seeks to explain interpatient variability in response to medications by investigating genotype-phenotype correlations. There is a small but growing body of data regarding the pharmacogenetics of both nonexudative and exudative age-related macular degeneration. Most reported data con...

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Bibliographic Details
Main Authors: Stephen G. Schwartz, Milam A. Brantley
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2011/252549
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spelling doaj-763a44c3bd7a49e6aabc7201aca176a82020-11-25T00:07:57ZengHindawi LimitedJournal of Ophthalmology2090-004X2090-00582011-01-01201110.1155/2011/252549252549Pharmacogenetics and Age-Related Macular DegenerationStephen G. Schwartz0Milam A. Brantley1Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 311 9th Street North, No. 100, Naples, FL 34102, USAVanderbilt Eye Institute, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN 37232, USAPharmacogenetics seeks to explain interpatient variability in response to medications by investigating genotype-phenotype correlations. There is a small but growing body of data regarding the pharmacogenetics of both nonexudative and exudative age-related macular degeneration. Most reported data concern polymorphisms in the complement factor H and age-related maculopathy susceptibility 2 genes. At this time, the data are not consistent and no definite conclusions may be drawn. As clinical trials data continue to accumulate, these relationships may become more apparent.http://dx.doi.org/10.1155/2011/252549
collection DOAJ
language English
format Article
sources DOAJ
author Stephen G. Schwartz
Milam A. Brantley
spellingShingle Stephen G. Schwartz
Milam A. Brantley
Pharmacogenetics and Age-Related Macular Degeneration
Journal of Ophthalmology
author_facet Stephen G. Schwartz
Milam A. Brantley
author_sort Stephen G. Schwartz
title Pharmacogenetics and Age-Related Macular Degeneration
title_short Pharmacogenetics and Age-Related Macular Degeneration
title_full Pharmacogenetics and Age-Related Macular Degeneration
title_fullStr Pharmacogenetics and Age-Related Macular Degeneration
title_full_unstemmed Pharmacogenetics and Age-Related Macular Degeneration
title_sort pharmacogenetics and age-related macular degeneration
publisher Hindawi Limited
series Journal of Ophthalmology
issn 2090-004X
2090-0058
publishDate 2011-01-01
description Pharmacogenetics seeks to explain interpatient variability in response to medications by investigating genotype-phenotype correlations. There is a small but growing body of data regarding the pharmacogenetics of both nonexudative and exudative age-related macular degeneration. Most reported data concern polymorphisms in the complement factor H and age-related maculopathy susceptibility 2 genes. At this time, the data are not consistent and no definite conclusions may be drawn. As clinical trials data continue to accumulate, these relationships may become more apparent.
url http://dx.doi.org/10.1155/2011/252549
work_keys_str_mv AT stephengschwartz pharmacogeneticsandagerelatedmaculardegeneration
AT milamabrantley pharmacogeneticsandagerelatedmaculardegeneration
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