Monte Carlo simulation of OLS and linear mixed model inference of phenotypic effects on gene expression
Background Self-contained tests estimate and test the association between a phenotype and mean expression level in a gene set defined a priori. Many self-contained gene set analysis methods have been developed but the performance of these methods for phenotypes that are continuous rather than discre...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2016-10-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/2575.pdf |