Integrating thermodynamic and sequence contexts improves protein-RNA binding prediction.

Predicting RNA-binding protein (RBP) specificity is important for understanding gene expression regulation and RNA-mediated enzymatic processes. It is widely believed that RBP binding specificity is determined by both the sequence and structural contexts of RNAs. Existing approaches, including tradi...

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Bibliographic Details
Main Authors: Yufeng Su, Yunan Luo, Xiaoming Zhao, Yang Liu, Jian Peng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007283

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