Occurrence and Antigenic Specificity of Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (P-ANCA) in Systemic Autoimmune Diseases

Occurrence and Antigenic Specificity of Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (P-ANCA) in Systemic Autoimmune Diseases

Perinuclear anti-neutrophilic cytoplasmic antibodies (P-ANCA) recognize heterogeneous antigens, including myeloperoxidase (MPO), lactoferrin, elastase, cathepsin-G and bactericidal/permeability-increasing protein. Although P-ANCA have diagnostic utility in vasculitides, they may also be found in pat...

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Bibliographic Details
Main Authors: Ourania D. Argyropoulou, Andreas V. Goules, Georgios Boutzios, Alexandra Tsirogianni, Charalampos Sfontouris, Menelaos N. Manoussakis, Panayiotis G. Vlachoyiannopoulos, Athanasios G. Tzioufas, Efstathia K. Kapsogeorgou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
P-ANCA autoantibodies
myeloperoxidase
elastase
vasculitis
systemic autoimmune rheumatic diseases
Online Access:https://www.mdpi.com/2073-4409/10/8/2128

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