FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells

FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells

Previous studies have established the pathogenic role of advanced glycation end products (AGEs) accumulation in intervertebral disc degeneration (IDD). Emerging evidence indicates that ER-phagy serves as a crucial cellular adaptive mechanism during stress conditions. This study is aimed at investiga...

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Bibliographic Details
Main Authors:	Rongjin Luo, Shuai Li, Gaocai Li, Saideng Lu, Weifeng Zhang, Hui Liu, Jie Lei, Liang Ma, Wencan Ke, Zhiwei Liao, Bingjin Wang, Yu Song, Kun Wang, Yukun Zhang, Cao Yang
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2021/3843145

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