Cell models of arrhythmogenic cardiomyopathy: advances and opportunities

Cell models of arrhythmogenic cardiomyopathy: advances and opportunities

Arrhythmogenic cardiomyopathy is a rare genetic disease that is mostly inherited as an autosomal dominant trait. It is associated predominantly with mutations in desmosomal genes and is characterized by the replacement of the ventricular myocardium with fibrous fatty deposits, arrhythmias and a high...

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Bibliographic Details
Main Authors: Elena Sommariva, Ilaria Stadiotti, Gianluca L. Perrucci, Claudio Tondo, Giulio Pompilio
Format: Article
Language:English
Published: The Company of Biologists 2017-07-01
Series:Disease Models & Mechanisms
Subjects:
Arrhythmogenic cardiomyopathy
ACM
ARVC
Cell models
In vitro
Molecular mechanisms
Online Access:http://dmm.biologists.org/content/10/7/823

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