Laser-assisted delivery enhances topical uptake of the anticancer agent cisplatin

Laser-assisted delivery enhances topical uptake of the anticancer agent cisplatin

Systemic chemotherapy with the anticancer agent cisplatin is approved for advanced non-melanoma skin cancer (NMSC), but topical treatment is limited by insufficient cutaneous penetration. We studied the impact of ablative fractional laser (AFL) exposure on topical cisplatin’s pharmacokinetics and bi...

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Bibliographic Details
Main Authors: Emily Wenande, Uffe H. Olesen, Malene R. Boesen, Daniel P. Persson, Catharina M. Lerche, Stefan Stürup, Bente Gammelgaard, Søren Husted, R. Rox Anderson, Merete Haedersdal
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
element bioimaging
fractional ablative co2 laser
laser-assisted drug delivery
local chemotherapy
non-melanoma skin cancer
Online Access:http://dx.doi.org/10.1080/10717544.2018.1534896

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