Novel Gene Fusions in Glioblastoma Tumor Tissue and Matched Patient Plasma

Novel Gene Fusions in Glioblastoma Tumor Tissue and Matched Patient Plasma

Sequencing studies have provided novel insights into the heterogeneous molecular landscape of glioblastoma (GBM), unveiling a subset of patients with gene fusions. Tissue biopsy is highly invasive, limited by sampling frequency and incompletely representative of intra-tumor heterogeneity. Extracellu...

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Bibliographic Details
Main Authors: Lan Wang, Anudeep Yekula, Koushik Muralidharan, Julia L. Small, Zachary S. Rosh, Keiko M. Kang, Bob S. Carter, Leonora Balaj
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
glioblastoma
gene fusions
liquid biopsy
RNA-seq
extracellular vesicles
Online Access:https://www.mdpi.com/2072-6694/12/5/1219

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