Formulation and Characterization of Acetazolamide/Carvedilol Niosomal Gel for Glaucoma Treatment: In Vitro and In Vivo Study

Formulation and Characterization of Acetazolamide/Carvedilol Niosomal Gel for Glaucoma Treatment: In Vitro and In Vivo Study

Acetazolamide (ACZ) is a diuretic used in glaucoma treatment; it has many side effects. Carvedilol (CAR) is a non-cardioselective beta-blocker used in the treatment of elevated intraocular pressure; it is subjected to the first-pass metabolism and causes fluids accumulation leading to edema. This st...

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Bibliographic Details
Main Authors: Rehab Abdelmonem, Sammar F. Elhabal, Nevine S. Abdelmalak, Mohamed A. El-Nabarawi, Mahmoud H. Teaima
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
acetazolamide
carvedilol
niosomes
gel
intraocular pressure
glaucoma
Online Access:https://www.mdpi.com/1999-4923/13/2/221

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https://www.mdpi.com/1999-4923/13/2/221

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