Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates

Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates

Common variable immunodeficiency (CVID) is a clinically and genetically heterogeneous disorder with inadequate antibody responses and low levels of immunoglobulins including IgA that is involved in the maintenance of the intestinal homeostasis. In this study, we analyzed the taxonomical and function...

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Bibliographic Details
Main Authors: Juraj Bosák, Matej Lexa, Kristýna Fiedorová, Darshak C. Gadara, Lenka Micenková, Zdenek Spacil, Jiří Litzman, Tomáš Freiberger, David Šmajs
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency
CVID
microbiome
metagenome
metabolome
Hungatella hathewayi
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.671239/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.671239/full

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