Toxicity and Antitumor Activity of a Thiophene–Acridine Hybrid

Toxicity and Antitumor Activity of a Thiophene–Acridine Hybrid

The antitumor effects of thiophene and acridine compounds have been described; however, the clinical usefulness of these compounds is limited due to the risk of high toxicity and drug resistance. The strategy of molecular hybridization presents the opportunity to develop new drugs which may display...

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Bibliographic Details
Main Authors: Thaís Lisboa, Daiana Silva, Sâmia Duarte, Rafael Ferreira, Camyla Andrade, Ana Luiza Lopes, Juliana Ribeiro, Davi Farias, Ricardo Moura, Malu Reis, Karina Medeiros, Hemerson Magalhães, Marianna Sobral
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
colorectal cancer
thiophene–acridine compound
antitumor
cytotoxicity
toxicity
Online Access:https://www.mdpi.com/1420-3049/25/1/64

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