Bioactive nanoparticle-based formulations increase survival area of perforator flaps in a rat model.

BACKGROUND:Distal flap necrosis is a frequent complication of perforator flaps. Advances in nanotechnology offer exciting new therapeutic approaches. Anti-inflammatory and neo-angiogenic properties of certain metal oxides within the nanoparticles, including bioglass and ceria, may promote flap survi...

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Bibliographic Details
Main Authors: Ioana Lese, David Alexander Graf, Catherine Tsai, Adriano Taddeo, Martin Tobias Matter, Mihai A Constantinescu, Inge Katrin Herrmann, Radu Olariu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6258121?pdf=render