Xylazine Activates Adenosine Monophosphate-Activated Protein Kinase Pathway in the Central Nervous System of Rats.

Xylazine is a potent analgesic extensively used in veterinary and animal experimentation. Evidence exists that the analgesic effect can be inhibited using adenosine 5'-monophosphate activated protein kinase (AMPK) inhibitors. Considering this idea, the aim of this study was to investigate wheth...

Full description

Bibliographic Details
Main Authors: Xing-Xing Shi, Bai-Shuang Yin, Peng Yang, Hao Chen, Xin Li, Li-Xue Su, Hong-Gang Fan, Hong-Bin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4822969?pdf=render