The Molecular Tweezer CLR01 Inhibits Antibody-Resistant Cell-to-Cell Spread of Human Cytomegalovirus

The Molecular Tweezer CLR01 Inhibits Antibody-Resistant Cell-to-Cell Spread of Human Cytomegalovirus

Human cytomegalovirus (HCMV) uses two major ways for virus dissemination: infection by cell-free virus and direct cell-to-cell spread. Neutralizing antibodies can efficiently inhibit infection by cell-free virus but mostly fail to prevent cell-to-cell transmission. Here, we show that the ‘molecular...

Full description

Bibliographic Details
Main Authors: Sina Brenner, Berenike Braun, Clarissa Read, Tatjana Weil, Paul Walther, Thomas Schrader, Jan Münch, Jens von Einem
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
cell-to-cell spread
HCMV
tweezer
CLR01
herpesvirus
inhibition
Online Access:https://www.mdpi.com/1999-4915/13/9/1685

Internet

https://www.mdpi.com/1999-4915/13/9/1685

Similar Items