Synthesis and NMR studies of malonyl-linked glycoconjugates of N-(2-aminoethyl)glycine. Building blocks for the construction of combinatorial glycopeptide libraries

Synthesis and NMR studies of malonyl-linked glycoconjugates of N-(2-aminoethyl)glycine. Building blocks for the construction of combinatorial glycopeptide libraries

Four glycoconjugate building blocks for the construction of combinatorial PNA like glycopeptide libraries were prepared in 75–79% yield by condensing tert-butyl N-[2-(N-9-fluorenylmethoxycarbonylamino)ethyl]glycinate (AEG) 5 with 3-oxo-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosylamino)- (6a), 3-oxo-...

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Bibliographic Details
Main Authors: Markus Nörrlinger, Sven Hafner, Thomas Ziegler
Format: Article
Language:English
Published: Beilstein-Institut 2016-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
amino acids
carbohydrates
glycoconjugates
glycopeptides
N-(2-aminoethyl)glycine
Online Access:https://doi.org/10.3762/bjoc.12.183

Internet

https://doi.org/10.3762/bjoc.12.183

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