Camel milk as an alternative treatment regimen for diabetes therapy

Abstract Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk i...

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Main Authors: Humaira Hussain, Feroza Hamid Wattoo, Muhammad Hamid Sarwar Wattoo, Muhammad Gulfraz, Tariq Masud, Imam Shah, Sakhawat Ali, Seyed Ebrahim Alavi
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Food Science & Nutrition
Subjects:
Online Access:https://doi.org/10.1002/fsn3.2078
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spelling doaj-75b54e9d5c39456d85f052b8f8b457662021-03-15T12:34:28ZengWileyFood Science & Nutrition2048-71772021-03-01931347135610.1002/fsn3.2078Camel milk as an alternative treatment regimen for diabetes therapyHumaira Hussain0Feroza Hamid Wattoo1Muhammad Hamid Sarwar Wattoo2Muhammad Gulfraz3Tariq Masud4Imam Shah5Sakhawat Ali6Seyed Ebrahim Alavi7University Institute of Biochemistry and Biotechnology PMAS ‐ Arid Agriculture University Rawalpindi PakistanUniversity Institute of Biochemistry and Biotechnology PMAS ‐ Arid Agriculture University Rawalpindi PakistanDepartment of Chemistry Pakistan Institute of Engineering and Applied Sciences Islamabad PakistanUniversity Institute of Biochemistry and Biotechnology PMAS ‐ Arid Agriculture University Rawalpindi PakistanDepartment of Food Technology PMAS ‐ Arid Agriculture University Rawalpindi PakistanNational Veterinary Laboratories Islamabad PakistanNational Veterinary Laboratories Islamabad PakistanDepartment of Pilot Nanobiotechnology Pasteur Institute of Iran Tehran IranAbstract Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c (p < .001), aspartate transaminase (AST), alanine transaminase (ALT) (p < .01), triglyceride (TG), and cholesterol (p < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.https://doi.org/10.1002/fsn3.2078antidiabetic activityglibenclamidehepatoprotective effecttriglyceride
collection DOAJ
language English
format Article
sources DOAJ
author Humaira Hussain
Feroza Hamid Wattoo
Muhammad Hamid Sarwar Wattoo
Muhammad Gulfraz
Tariq Masud
Imam Shah
Sakhawat Ali
Seyed Ebrahim Alavi
spellingShingle Humaira Hussain
Feroza Hamid Wattoo
Muhammad Hamid Sarwar Wattoo
Muhammad Gulfraz
Tariq Masud
Imam Shah
Sakhawat Ali
Seyed Ebrahim Alavi
Camel milk as an alternative treatment regimen for diabetes therapy
Food Science & Nutrition
antidiabetic activity
glibenclamide
hepatoprotective effect
triglyceride
author_facet Humaira Hussain
Feroza Hamid Wattoo
Muhammad Hamid Sarwar Wattoo
Muhammad Gulfraz
Tariq Masud
Imam Shah
Sakhawat Ali
Seyed Ebrahim Alavi
author_sort Humaira Hussain
title Camel milk as an alternative treatment regimen for diabetes therapy
title_short Camel milk as an alternative treatment regimen for diabetes therapy
title_full Camel milk as an alternative treatment regimen for diabetes therapy
title_fullStr Camel milk as an alternative treatment regimen for diabetes therapy
title_full_unstemmed Camel milk as an alternative treatment regimen for diabetes therapy
title_sort camel milk as an alternative treatment regimen for diabetes therapy
publisher Wiley
series Food Science & Nutrition
issn 2048-7177
publishDate 2021-03-01
description Abstract Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c (p < .001), aspartate transaminase (AST), alanine transaminase (ALT) (p < .01), triglyceride (TG), and cholesterol (p < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.
topic antidiabetic activity
glibenclamide
hepatoprotective effect
triglyceride
url https://doi.org/10.1002/fsn3.2078
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