Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma

Introduction. Soft tissue tumors around the knee joint still pose problems for the excision and subsequent reconstruction. Methods. In the 6 included patients the soft tissue sarcoma has its base on the anterior surface of the extensor mechanism and expands towards the skin. The entire extensor appa...

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Main Authors: Daniel A. Müller, Giovanni Beltrami, Guido Scoccianti, Pierluigi Cuomo, Francesca Totti, Rodolfo Capanna
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Advances in Orthopedics
Online Access:http://dx.doi.org/10.1155/2018/6275861
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spelling doaj-75a840aa25bc4b77a6e6cbaa6b1457b12020-11-24T20:45:51ZengHindawi LimitedAdvances in Orthopedics2090-34642090-34722018-01-01201810.1155/2018/62758616275861Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue SarcomaDaniel A. Müller0Giovanni Beltrami1Guido Scoccianti2Pierluigi Cuomo3Francesca Totti4Rodolfo Capanna5Department of Orthopedic Surgery, Balgrist University Hospital, Forchstrasse 340, 8008 Zürich, SwitzerlandDepartment of Orthopedic Oncology, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyDepartment of Orthopedic Oncology, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyDepartment of Orthopedic Oncology, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyDepartment of Orthopedic Oncology, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyDepartment of Orthopedic Surgery, Azienda Ospedaliero-Universitaria Pisana, Via Paradisa 2, Cisanello, 56125 Pisa, ItalyIntroduction. Soft tissue tumors around the knee joint still pose problems for the excision and subsequent reconstruction. Methods. In the 6 included patients the soft tissue sarcoma has its base on the anterior surface of the extensor mechanism and expands towards the skin. The entire extensor apparatus (quadriceps tendon, patella, and patellar tendon) was resected and replaced by a fresh-frozen allograft. Results. The mean follow-up was 6.7 years (range: 2–12.4 years). In two patients a local recurrence occurred, resulting in a 5-year local recurrence-free rate of 66.7% (95% CI: 19.5%–90.4%). Distant metastases were found in 4 patients resulting in a 5-year metastasis-free rate of 33.3% (95% CI: 4.6%–67.5%). Two patients underwent at least one revision surgery, including one patient in whom the allograft had to be removed. According to the ISOLS function score 24.7 points (range: 19–28 points) were achieved at the last follow-up. The mean active flexion of the knee joint was 82.5° (range: 25–120°) and a mean extension lag of 10° (range: 0–30°) was observed. Conclusions. The replacement of the extensor mechanism by an allograft is a reasonable option, allowing wide margins and restoration of active extension in most patients. Trial Registration. The presented study is listed on the ISRCTN registry with trial number ISRCTN63060594.http://dx.doi.org/10.1155/2018/6275861
collection DOAJ
language English
format Article
sources DOAJ
author Daniel A. Müller
Giovanni Beltrami
Guido Scoccianti
Pierluigi Cuomo
Francesca Totti
Rodolfo Capanna
spellingShingle Daniel A. Müller
Giovanni Beltrami
Guido Scoccianti
Pierluigi Cuomo
Francesca Totti
Rodolfo Capanna
Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma
Advances in Orthopedics
author_facet Daniel A. Müller
Giovanni Beltrami
Guido Scoccianti
Pierluigi Cuomo
Francesca Totti
Rodolfo Capanna
author_sort Daniel A. Müller
title Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma
title_short Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma
title_full Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma
title_fullStr Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma
title_full_unstemmed Allograft Reconstruction of the Extensor Mechanism after Resection of Soft Tissue Sarcoma
title_sort allograft reconstruction of the extensor mechanism after resection of soft tissue sarcoma
publisher Hindawi Limited
series Advances in Orthopedics
issn 2090-3464
2090-3472
publishDate 2018-01-01
description Introduction. Soft tissue tumors around the knee joint still pose problems for the excision and subsequent reconstruction. Methods. In the 6 included patients the soft tissue sarcoma has its base on the anterior surface of the extensor mechanism and expands towards the skin. The entire extensor apparatus (quadriceps tendon, patella, and patellar tendon) was resected and replaced by a fresh-frozen allograft. Results. The mean follow-up was 6.7 years (range: 2–12.4 years). In two patients a local recurrence occurred, resulting in a 5-year local recurrence-free rate of 66.7% (95% CI: 19.5%–90.4%). Distant metastases were found in 4 patients resulting in a 5-year metastasis-free rate of 33.3% (95% CI: 4.6%–67.5%). Two patients underwent at least one revision surgery, including one patient in whom the allograft had to be removed. According to the ISOLS function score 24.7 points (range: 19–28 points) were achieved at the last follow-up. The mean active flexion of the knee joint was 82.5° (range: 25–120°) and a mean extension lag of 10° (range: 0–30°) was observed. Conclusions. The replacement of the extensor mechanism by an allograft is a reasonable option, allowing wide margins and restoration of active extension in most patients. Trial Registration. The presented study is listed on the ISRCTN registry with trial number ISRCTN63060594.
url http://dx.doi.org/10.1155/2018/6275861
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