Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach

Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach

Bibliographic Details
Main Authors:	Maga Giovanni, Garbelli Anna, Radi Marco, Falchi Federico, Samuele Alberta, Paolucci Stefania, Baldanti Fausto, Manetti Fabrizio, Beermann Sandra, Dietrich Ursula, Botta Maurizio
Format:	Article
Language:	English
Published:	BMC 2012-05-01
Series:	Retrovirology

Similar Items

Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase
by: Baldanti Fausto, et al.
Published: (2010-05-01)

A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication.
by: Anna Garbelli, et al.
Published: (2011-01-01)

Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
by: Annalaura Brai, et al.
Published: (2019-11-01)

Novel Insights into the Biochemical Mechanism of CK1ε and its Functional Interplay with DDX3X
by: Bartolo Bono, et al.
Published: (2020-09-01)

Human helicase DDX3 as target for broad-spectrum antivirals against pandemic and emerging viruses
by: Annalaura Brai, et al.
Published: (2016-05-01)

HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients
by: Comolli Giuditta, et al.
Published: (2011-03-01)

Genetic divergence of influenza A NS1 gene in pandemic 2009 H1N1 isolates with respect to H1N1 and H3N2 isolates from previous seasonal epidemics
by: Campanini Giulia, et al.
Published: (2010-09-01)

Next-Generation Sequencing of DDX41 in Myeloid Neoplasms Leads to Increased Detection of Germline Alterations
by: Sarah A. Bannon, et al.
Published: (2021-01-01)

Rôle des ARN hélicases Ddx5 et Ddx17 dans la progression tumorale
by: Dardenne, Étienne
Published: (2014)

The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection.
by: Laura Bavagnoli, et al.
Published: (2011-01-01)

Oncogenic properties of the DDX1 gene
by: Elsden, Joanna Louise
Published: (2004)

HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate
by: Giovanni Maga, et al.
Published: (2010-03-01)

Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins
by: Flavia Squeglia, et al.
Published: (2020-12-01)

DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs
by: Marina K. Kukhanova, et al.
Published: (2020-02-01)

RNA Helicases DDX5 and DDX17 Dynamically Orchestrate Transcription, miRNA, and Splicing Programs in Cell Differentiation
by: Etienne Dardenne, et al.
Published: (2014-06-01)

Waltzing around cofactors
by: Percival Yang-Ting Chen, et al.
Published: (2016-02-01)

Peroxisomal Cofactor Transport
by: Anastasija Plett, et al.
Published: (2020-08-01)

Waltzing around cofactors
by: Wittenborn, Elizabeth Charlot, et al.
Published: (2016)

Construct Binary Decision DiagrambyCofactor on Circuit Structure by Cofactor on Circuit Structure
by: Tsung-Mao Lin, et al.
Published: (2007)

On the Metal Cofactor in the Tyrosinase Family
by: Francisco Solano
Published: (2018-02-01)

Arginine cofactors on the polymerase ribozyme.
by: Chengguo Yao, et al.
Published: (2011-01-01)

Molybdenum-Cofactor Deficiency and Seizures
by: J Gordon Millichap
Published: (1993-07-01)

Deciphering The Role of DDX21 in EBV Induced Pathogenesis
by: Lin, Jou-An, et al.
Published: (2018)

Molecular Analyses of DDX41 in the Spliceosome and Myeloid Neoplasms
by: Hiznay, James Matthew
Published: (2019)

DDX3X: structure, physiologic functions and cancer
by: Jie Mo, et al.
Published: (2021-02-01)

Growth by Insertion: The Family of Bacterial DDxP Proteins
by: Pierpaolo Di Nocera, et al.
Published: (2020-12-01)

The emerging roles of the DDX41 protein in immunity and diseases
by: Yan Jiang, et al.
Published: (2016-08-01)

Study on the role of DDX3 in mRNA export
by: Kuo Chu-Yun, et al.
Published: (2008)

Study on the Biological Roles of DDX3 in Colorectal Cancer
by: I-Chun Chang Chien, et al.
Published: (2011)

Physiopathological role of Ddx3x in mammary gland
by: Shu-Ting Hsu, et al.
Published: (2015)

Sex Determination of Cattle Meat by Polymerase Chain Reaction Amplification of the DEAD Box Protein (DDX3X/DDX3Y) Gene
by: P. Gokulakrishnan, et al.
Published: (2012-05-01)

Studies of the Xcc Hrp regulatory protein FhrR and human innate immunity dsRNA receptor protein DDX1-DDX21 complex
by: Ya-Ting Yu, et al.
Published: (2013)

Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells
by: Rosa Muñoz-Cano, et al.
Published: (2021-02-01)

Exploiting the Nucleotide Substrate Specificity of Repair DNA Polymerases To Develop Novel Anticancer Agents
by: Giovanni Maga, et al.
Published: (2011-09-01)

Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis
by: Matteo Caforio, et al.
Published: (2018-09-01)

Functional Role of Ddx3x in mouse colorectal epithelium
by: Hua-Bang Wang, et al.
Published: (2017)

Functional roles of DDX3X in cardiovascular development and hematopoiesis
by: Jing-Yi Hu, et al.
Published: (2018)

Plasmodium falciparum DDX31 is DNA helicase localized in nucleolus
by: Rahena Yasmin, et al.
Published: (2019-12-01)

DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes
by: Jennifer H. Lumb, et al.
Published: (2017-07-01)

DDX5 RNA Helicases: Emerging Roles in Viral Infection
by: Wenyu Cheng, et al.
Published: (2018-04-01)