Cerebral infarction caused by systemic sclerosis: a case report

Systemic sclerosis, also known as scleroderma, is a rare multisystem autoimmune disease characterized by vascular lesions caused by collagen deposition in the skin and viscera and damage to the endothelium. Endothelial injury and microvascular occlusion result in Raynaud’s phenomenon, finger ischemi...

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Bibliographic Details
Main Authors: Qingqing Wang, Mengen Zhang, Mingfeng Zhai, Zongyou Li
Format: Article
Language:English
Published: SAGE Publishing 2021-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211044045
Description
Summary:Systemic sclerosis, also known as scleroderma, is a rare multisystem autoimmune disease characterized by vascular lesions caused by collagen deposition in the skin and viscera and damage to the endothelium. Endothelial injury and microvascular occlusion result in Raynaud’s phenomenon, finger ischemia, pulmonary hypertension, and scleroderma renal crisis. Scleroderma itself is a rare disease with an incidence ranging from 0.1 to 14 per 100,000 people in the general population. Cerebral involvement is not considered a common manifestation of systemic sclerosis, although studies have shown that the brain can be involved. Therefore, to deepen the understanding of this disease, we herein report a case of cerebral infarction associated with systemic sclerosis.
ISSN:1473-2300