Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells

Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells

Microglia are resident tissue macrophages of the central nervous system (CNS) that arise from erythromyeloid progenitors during embryonic development. They play essential roles in CNS development, homeostasis and response to disease. Since microglia are difficult to procure from the human brain, sev...

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Bibliographic Details
Main Authors: Poulomi Banerjee, Evdokia Paza, Emma M. Perkins, Owen G. James, Boyd Kenkhuis, Amy F. Lloyd, Karen Burr, David Story, Dilmurat Yusuf, Xin He, Rolf Backofen, Owen Dando, Siddharthan Chandran, Josef Priller
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Subjects:
Nervous system
Myeloid cells
Microglia
Transcriptome
Organoid
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303470

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