Imaging of complications from hematopoietic stem cell transplant

• Main Authors: Tarun Pandey, Suresh Maximin, Puneet Bhargava
• Format: Article
• Language: English
• Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2014-11-01
• Series: Indian Journal of Radiology and Imaging
• Subjects: complications; hematopoietic stem cell; imaging; intervention; radiology; stem cell
• Online Access: http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.143895

Stem cell transplant has been the focus of clinical research for a long time given its potential to treat several incurable diseases like hematological malignancies, diabetes mellitus, and neuro-degenerative disorders like Parkinson disease. Hematopoietic stem cell transplantation (HSCT) is the oldest and most widely used technique of stem cell transplant. HSCT has not only been used to treat hematological disorders including hematological malignancies, but has also been found useful in treamtent of genetic, immunological, and solid tumors like neuroblastoma, lymphoma, and germ cell tumors. In spite of the rapid advances in stem cell technology, success rate with this technique has not been universal and many complications have also been seen with this form of therapy. The key to a successful HSCT therapy lies in early diagnosis and effective management of complications associated with this treatment. Our article aims to review the role of imaging in diagnosis and management of stem cell transplant complications associated with HSCT.