Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment
<p>Abstract</p><p>Time and resource constraints necessitate increasingly early decisions to advance or halt pre-clinical drug discovery programs. Early discovery or “tool” compounds may be potent inhibitors of new targets, but all too often they exhibit poor pha...
Main Authors: | Chiang Po-Chang, Ghosh Sarbani, Roberds Steven, Wahlstrom Jan, Warren Chad, Wene Steve, Albin Lesley, Smith Mark |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2007-01-01
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Series: | Nanoscale Research Letters |
Subjects: | |
Online Access: | http://dx.doi.org/10.1007/s11671-007-9063-7 |
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