Up-regulation of GITRL on dendritic cells by WGP improves anti-tumor immunity in murine Lewis lung carcinoma.

BACKGROUND: β-Glucans have been shown to function as a potent immunomodulator to stimulate innate and adaptive immune responses, which contributes to their anti-tumor property. However, their mechanisms of action are still elusive. Glucocorticoid-induced TNF receptor ligand (GITRL), a member of the...

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Bibliographic Details
Main Authors: Jie Tian, Jie Ma, Ke Ma, Bin Ma, Xinyi Tang, Samuel Essien Baidoo, Jia Tong, Jun Yan, Liwei Lu, Huaxi Xu, Shengjun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471954?pdf=render