Docosahexaenoic fatty acid reduces the pro‐inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation

Docosahexaenoic fatty acid reduces the pro‐inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation

Abstract Background Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurological pathologies may exacerbate neurodegenerative processes. Accumulating...

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Bibliographic Details
Main Authors: Emilia Zgórzyńska, Dawid Stulczewski, Barbara Dziedzic, Kuan-Pin Su, Anna Walczewska
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Neuroscience
Subjects:
Neuroinflammation
Astrocytes
Docosahexaenoic acid
Online Access:https://doi.org/10.1186/s12868-021-00611-w

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