PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration.
The planar cell polarity (PCP) pathway is a cell-contact mediated mechanism for transmitting polarity information between neighboring cells. PCP "core components" (Vangl, Fz, Pk, Dsh, and Celsr) are essential for a number of cell migratory events including the posterior migration of facial...
Main Authors: | Crystal F Davey, Andrew W Mathewson, Cecilia B Moens |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-03-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4798406?pdf=render |
Similar Items
-
The neuroepithelial basement membrane serves as a boundary and a substrate for neuron migration in the zebrafish hindbrain
by: Grant Paul K, et al.
Published: (2010-03-01) -
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
by: Cheng Cui, et al.
Published: (2013-11-01) -
Generation of Planar Cell Polarity (PCP) in vitro for Epithelium Tissue Engineering
by: Paz Mejia, Ana Cristina
Published: (2011) -
Generation of Planar Cell Polarity (PCP) in vitro for Epithelium Tissue Engineering
by: Paz Mejia, Ana Cristina
Published: (2011) -
Directed Migration of Pulmonary Neuroendocrine Cells toward Airway Branches Organizes the Stereotypic Location of Neuroepithelial Bodies
by: Masafumi Noguchi, et al.
Published: (2015-12-01)