Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation?
A 20-week fetus was diagnosed with tetralogy of Fallot and multicystic kidneys. The postmortem study showed missing müllerian structures with small streak ovaries, external male genitalia, and an abnormal cloacal septation (imperforate anus with a sigmoid colon opening in the bladder). As the obser...
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Hindawi Limited
2012-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2012/502919 |
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doaj-756715cf0cc6490fb4c52b196c4ebc562020-11-24T23:24:05ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66842090-66922012-01-01201210.1155/2012/502919502919Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation?José Morales-Roselló0Teresa Escudero Serrano1Ana García Almela2Rafael Lázaro Santander3Servicio de Obstetricia y Ginecología, Hospital de la Plana, Villarreal, SpainServicio de Obstetricia y Ginecología, Hospital de la Plana, Villarreal, SpainServicio de Obstetricia y Ginecología, Hospital de la Plana, Villarreal, SpainServicio de Anatomía Patológica, Hospital de la Plana, Villarreal, SpainA 20-week fetus was diagnosed with tetralogy of Fallot and multicystic kidneys. The postmortem study showed missing müllerian structures with small streak ovaries, external male genitalia, and an abnormal cloacal septation (imperforate anus with a sigmoid colon opening in the bladder). As the observed anomalies were related with septation, a mechanism related with the activation of specific growth factors, we discuss the possibility of a disorder in the function of the bone morphogenetic proteins as a common cause for the widespread anomalies found in this fetus.http://dx.doi.org/10.1155/2012/502919 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
José Morales-Roselló Teresa Escudero Serrano Ana García Almela Rafael Lázaro Santander |
| spellingShingle |
José Morales-Roselló Teresa Escudero Serrano Ana García Almela Rafael Lázaro Santander Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation? Case Reports in Obstetrics and Gynecology |
| author_facet |
José Morales-Roselló Teresa Escudero Serrano Ana García Almela Rafael Lázaro Santander |
| author_sort |
José Morales-Roselló |
| title |
Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation? |
| title_short |
Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation? |
| title_full |
Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation? |
| title_fullStr |
Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation? |
| title_full_unstemmed |
Tetralogy of Fallot Associated with Dysplastic Kidneys, Cloacal Anomalies, and Female Pseudohermaphroditism: A Systemic Anomaly of Septation? |
| title_sort |
tetralogy of fallot associated with dysplastic kidneys, cloacal anomalies, and female pseudohermaphroditism: a systemic anomaly of septation? |
| publisher |
Hindawi Limited |
| series |
Case Reports in Obstetrics and Gynecology |
| issn |
2090-6684 2090-6692 |
| publishDate |
2012-01-01 |
| description |
A 20-week fetus was diagnosed with tetralogy of Fallot and multicystic kidneys. The postmortem study showed missing müllerian structures with small streak ovaries, external male genitalia, and an abnormal cloacal septation (imperforate anus with a sigmoid colon opening in the bladder).
As the observed anomalies were related with septation, a mechanism related with the activation of specific growth factors, we discuss the possibility of a disorder in the function of the bone morphogenetic proteins as a common cause for the widespread anomalies found in this fetus. |
| url |
http://dx.doi.org/10.1155/2012/502919 |
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