Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review

Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review

The air-stable hydride-platinum(II) complex [PtH{(PMe2O)2H}(PMe2OH)], reported by Parkins and co-workers in 1995, is the most versatile catalyst currently available for the hydration of C≡N bonds. It features remarkable activity under relatively mild conditions and exceptionally high functional grou...

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Bibliographic Details
Main Author: Victorio Cadierno
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Applied Sciences
Subjects:
homogeneous catalysis
hydration reactions
platinum
amides
nitriles
organic synthesis
Online Access:http://www.mdpi.com/2076-3417/5/3/380
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spelling doaj-75602cd02eb14e2c8beea69b99c752372020-11-24T21:07:56ZengMDPI AGApplied Sciences2076-34172015-08-015338040110.3390/app5030380app5030380Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A ReviewVictorio Cadierno0Laboratory of Organometallic Compounds and Catalysis (CSIC Associated Unit), Innovation Center in Advanced Chemistry (ORFEO-CINQA), Department of Organic and Inorganic Chemistry, Institute of Organometallic Chemistry "Enrique Moles", Faculty of Chemistry, University of Oviedo, Oviedo E-33006, SpainThe air-stable hydride-platinum(II) complex [PtH{(PMe2O)2H}(PMe2OH)], reported by Parkins and co-workers in 1995, is the most versatile catalyst currently available for the hydration of C≡N bonds. It features remarkable activity under relatively mild conditions and exceptionally high functional group compatibility, facts that have allowed the implementation of this complex in the synthesis of a large number of structurally complex, biologically active molecules and natural products. In this contribution, synthetic applications of the Parkins catalyst are reviewed.http://www.mdpi.com/2076-3417/5/3/380homogeneous catalysishydration reactionsplatinumamidesnitrilesorganic synthesis
collection DOAJ
language English
format Article
sources DOAJ
author Victorio Cadierno
spellingShingle Victorio Cadierno
Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review
Applied Sciences
homogeneous catalysis
hydration reactions
platinum
amides
nitriles
organic synthesis
author_facet Victorio Cadierno
author_sort Victorio Cadierno
title Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review
title_short Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review
title_full Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review
title_fullStr Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review
title_full_unstemmed Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review
title_sort synthetic applications of the parkins nitrile hydration catalyst [pth{(pme2o)2h}(pme2oh)]: a review
publisher MDPI AG
series Applied Sciences
issn 2076-3417
publishDate 2015-08-01
description The air-stable hydride-platinum(II) complex [PtH{(PMe2O)2H}(PMe2OH)], reported by Parkins and co-workers in 1995, is the most versatile catalyst currently available for the hydration of C≡N bonds. It features remarkable activity under relatively mild conditions and exceptionally high functional group compatibility, facts that have allowed the implementation of this complex in the synthesis of a large number of structurally complex, biologically active molecules and natural products. In this contribution, synthetic applications of the Parkins catalyst are reviewed.
topic homogeneous catalysis
hydration reactions
platinum
amides
nitriles
organic synthesis
url http://www.mdpi.com/2076-3417/5/3/380
work_keys_str_mv AT victoriocadierno syntheticapplicationsoftheparkinsnitrilehydrationcatalystpthpme2o2hpme2ohareview
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