Nonheritable cellular variability accelerates the evolutionary processes of cancer.

Nonheritable cellular variability accelerates the evolutionary processes of cancer.

Recent cancer studies emphasize that genetic and heritable epigenetic changes drive the evolutionary rate of cancer progression and drug resistance. We discuss the ways in which nonheritable aspects of cellular variability may significantly increase evolutionary rate. Nonheritable variability arises...

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Bibliographic Details
Main Authors:	Steven A Frank, Marsha Rich Rosner
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS Biology
Online Access:	http://europepmc.org/articles/PMC3317895?pdf=render

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