Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection.

Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection.

Galectin-3 is a β-galactoside-binding protein that has been shown to regulate pathophysiological processes, including cellular activation, differentiation and apoptosis. Recently, we showed that galectin-3 acts as a potent inhibitor of B cell differentiation into plasma cells. Here, we have investig...

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Bibliographic Details
Main Authors: Felipe L Oliveira, Camila Brand, Adelzon A Paula, Kátia D Arcanjo, Daniel K Hsu, Fu-Tong Liu, Christina M Takiya, Radovan Borojevic, Roger Chammas, Márcia C El-Cheikh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3089595?pdf=render

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