Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis

Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis

The IL-13Rα1 signaling pathway and M2 macrophages play crucial roles in schistosome egg-induced hepatic fibrosis via the expression of pro-fibrotic molecules. This study aims to investigate the inhibitory effect and mechanism of action of corilagin on schistosome egg-induced hepatic fibrosis via the...

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Bibliographic Details
Main Authors: Yi-Qing Li, Yun-Fei Chen, Yi-Ping Dang, Yao Wang, Zhen-Zhong Shang, Qian Ma, Yu-Jie Wang, Juan Zhang, Lei Luo, Quan-Qiang Li, Lei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
corilagin
liver fibrosis
schistosome egg
IL-13Rα1
M2 macrophage
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00443/full

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