Regulatory T cells and cytotoxic T cells close to the epithelial–stromal interface are associated with a favorable prognosis

Regulatory T cells and cytotoxic T cells close to the epithelial–stromal interface are associated with a favorable prognosis

Cytotoxic T cells and regulatory T cells play a crucial role in the outcome of cancer patients. Besides the density of these cells, it was shown recently that the spatial distribution is equally important. Here, we specifically analyzed the spatial distribution of these T cell subtypes at the epithe...

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Bibliographic Details
Main Authors: Julian Rudolf, Maike Büttner-Herold, Katharina Erlenbach-Wünsch, Rebecca Posselt, Jonas Jessberger, Marlen Haderlein, Markus Hecht, Arndt Hartmann, Rainer Fietkau, Luitpold Distel
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
cytotoxic t cells
regulatory t cells
spatial distribution
rectal cancer
epithelial–stromal interface
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1746149

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