Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation.

Genetic variation at the melanocortin 1 receptor (MC1R) is an important risk factor for developing ultraviolet (UV) radiation-induced skin cancer, the most common form of cancer in humans. The underlying mechanisms by which the MC1R defends against UV-induced skin cancer are not known. We used neona...

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Bibliographic Details
Main Authors: Craig S April, Gregory S Barsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1774588?pdf=render

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