Diagnostic Performance of Plasma DNA Methylation Profiles in Lung Cancer, Pulmonary Fibrosis and COPD

Diagnostic Performance of Plasma DNA Methylation Profiles in Lung Cancer, Pulmonary Fibrosis and COPD

Disease-specific alterations of the cell-free DNA methylation status are frequently found in serum samples and are currently considered to be suitable biomarkers. Candidate markers were identified by bisulfite conversion-based genome-wide methylation screening of lung tissue from lung cancer, fibrot...

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Bibliographic Details
Main Authors: Matthias Wielscher, Klemens Vierlinger, Ulrike Kegler, Rolf Ziesche, Andrea Gsur, Andreas Weinhäusel
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:EBioMedicine
Subjects:
Liquid biopsy
methyl-sensitive restriction enzyme
multiplex PCR
Biomarker
PAX9
HOXD10
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300530

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