Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke

Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke

Glutamate transport is the only mechanism for maintaining extracellular glutamate concentrations below excitotoxic levels. Among glutamate transporters, EAAT2 is responsible for up to 90% of all glutamate transport and has been reported to be associated to lipid rafts. In this context, we have recen...

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Bibliographic Details
Main Authors: O. Hurtado, J.M. Pradillo, D. Fernández-López, J.R. Morales, T. Sobrino, J. Castillo, E. Alborch, M.A. Moro, I. Lizasoain
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Neurobiology of Disease
Subjects:
Glutamate
Glutamate transporters
Ischemia
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610700191X

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