The Epoxy Group of Pramanicin Is Required for the Optimal Endothelium-Dependent Relaxation of Rat Aorta
The vascular effects of a newly discovered anti-fungal agent, pramanicin (PMC), and its two analogues, PMC-A, in which the epoxy group is replaced by a – HC = CH – bond, and PMC-B, on which the diene is converted to the saturated (CH2)4-derivative, respectively, were investigated in rat aorta. All t...
Main Authors: | Chiu-Yin Kwan, Wen-Bo Zhang, Joanna Miller, Paul H.M. Harrison, Salina Kassan, David Liscombe |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319326519 |
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