Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome

An alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea. The diagnosis of the alveolar hemorrhage was based on the presence of ac...

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Main Authors:	D. A. Vargas-Gutiérrez, F. Solís-Jiménez, K. I. Arias Callejas, L. Cano Cruz, R. Zapata Arenas, A. O. Acero López, P. Puente Rodríguez, S. Velázquez de la Paz
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Case Reports in Rheumatology
Online Access:	http://dx.doi.org/10.1155/2019/5453717

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spelling	doaj-754cc27515ce45048a11d7a6d78ee7092020-11-25T02:29:28ZengHindawi LimitedCase Reports in Rheumatology2090-68892090-68972019-01-01201910.1155/2019/54537175453717Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase SyndromeD. A. Vargas-Gutiérrez0F. Solís-Jiménez1K. I. Arias Callejas2L. Cano Cruz3R. Zapata Arenas4A. O. Acero López5P. Puente Rodríguez6S. Velázquez de la Paz7Internal Medicine Department, Hospital General de Mexico ‘Dr. Eduardo Liceaga’, Mexico City, MexicoInternal Medicine Department, Hospital General de Mexico ‘Dr. Eduardo Liceaga’, Mexico City, MexicoInternal Medicine Department, Hospital General de Mexico ‘Dr. Eduardo Liceaga’, Mexico City, MexicoRheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoInternal Medicine Department, Hospital General de Mexico ‘Dr. Eduardo Liceaga’, Mexico City, MexicoInternal Medicine Department, Hospital General de Mexico ‘Dr. Eduardo Liceaga’, Mexico City, MexicoSchool of Health Sciences, Anahuac University, Mexico City, MexicoMexican Medical School, La Salle University, Mexico City, MexicoAn alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea. The diagnosis of the alveolar hemorrhage was based on the presence of acute respiratory failure, decrease in hemoglobin levels, and observation of macrophages filled with hemosiderin. The antisynthetase syndrome was classified through a tomographic image compatible with a nonspecific interstitial pneumonia, along with antibodies associated to myositis (PL-12 and Ro-52). The study protocol was completed with the result of a myopathic pattern showed in electromyography. This patient presented a good response to steroids and disease-modifying antirheumatic drug (DMARD).http://dx.doi.org/10.1155/2019/5453717
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	D. A. Vargas-Gutiérrez F. Solís-Jiménez K. I. Arias Callejas L. Cano Cruz R. Zapata Arenas A. O. Acero López P. Puente Rodríguez S. Velázquez de la Paz
spellingShingle	D. A. Vargas-Gutiérrez F. Solís-Jiménez K. I. Arias Callejas L. Cano Cruz R. Zapata Arenas A. O. Acero López P. Puente Rodríguez S. Velázquez de la Paz Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome Case Reports in Rheumatology
author_facet	D. A. Vargas-Gutiérrez F. Solís-Jiménez K. I. Arias Callejas L. Cano Cruz R. Zapata Arenas A. O. Acero López P. Puente Rodríguez S. Velázquez de la Paz
author_sort	D. A. Vargas-Gutiérrez
title	Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
title_short	Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
title_full	Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
title_fullStr	Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
title_full_unstemmed	Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome
title_sort	diffuse alveolar hemorrhage in a patient with antisynthetase syndrome
publisher	Hindawi Limited
series	Case Reports in Rheumatology
issn	2090-6889 2090-6897
publishDate	2019-01-01
description	An alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea. The diagnosis of the alveolar hemorrhage was based on the presence of acute respiratory failure, decrease in hemoglobin levels, and observation of macrophages filled with hemosiderin. The antisynthetase syndrome was classified through a tomographic image compatible with a nonspecific interstitial pneumonia, along with antibodies associated to myositis (PL-12 and Ro-52). The study protocol was completed with the result of a myopathic pattern showed in electromyography. This patient presented a good response to steroids and disease-modifying antirheumatic drug (DMARD).
url	http://dx.doi.org/10.1155/2019/5453717
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Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome

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