Nafamostat Mesilate Induces Production of Interleukin-12 and -18 in Human Peripheral Blood Mononuclear Cells

Nafamostat Mesilate Induces Production of Interleukin-12 and -18 in Human Peripheral Blood Mononuclear Cells

Little has been reported on the drugs inducing production of monocyte-derived cytokines like interleukin (IL)-18 and IL-12. We found that nafamostat mesilate elicits IL-12, IL-18, tumor necrosis factor-α and interferon-γ production, and the expression of intercellular adhesion molecules-1, B7.1, B7....

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Bibliographic Details
Main Authors:	Goutarou Katsuno, Hideo K. Takahashi, Hiromi Iwagaki, Kenji Mizuno, Shuji Mori, Tadashi Yoshino, Masahiro Nishibori, Noriaki Tanaka
Format:	Article
Language:	English
Published:	Elsevier 2005-01-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861319321644

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