Oxytocin‐monomeric red fluorescent protein 1 synthesis in the hypothalamus under osmotic challenge and acute hypovolemia in a transgenic rat line

Oxytocin‐monomeric red fluorescent protein 1 synthesis in the hypothalamus under osmotic challenge and acute hypovolemia in a transgenic rat line

Abstract We generated a transgenic rat line that expresses oxytocin (OXT)‐monomeric red fluorescent protein 1 (mRFP1) fusion gene to visualize the dynamics of OXT. In this transgenic rat line, hypothalamic OXT can be assessed under diverse physiological and pathophysiological conditions by semiquant...

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Bibliographic Details
Main Authors: Hiromichi Ueno, Kenya Sanada, Tetsu Miyamoto, Kazuhiko Baba, Kentaro Tanaka, Haruki Nishimura, Kazuaki Nishimura, Satomi Sonoda, Mitsuhiro Yoshimura, Takashi Maruyama, Yasushi Oginosawa, Masaru Araki, Shinjo Sonoda, Tatsushi Onaka, Yutaka Otsuji, Yoichi Ueta
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Physiological Reports
Subjects:
hyperosmolality
hypothalamus
hypovolemia
oxytocin
transgenic rat
Online Access:https://doi.org/10.14814/phy2.14558

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