Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals.

Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals.

Broadly neutralizing antibodies may protect against HIV-1 acquisition. In natural infection, only 10-30% of patients have cross-reactive neutralizing humoral immunity which may relate to viral and or host factors. To explore the role of host genetic markers in the formation of cross-reactive neutral...

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Bibliographic Details
Main Authors: Zelda Euler, Marit J van Gils, Brigitte D Boeser-Nunnink, Hanneke Schuitemaker, Daniëlle van Manen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553002?pdf=render

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