Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.

Complement factor H-related protein 1 (CFHR1) is a complement regulator which has been reported to regulate complement by blocking C5 convertase activity and interfering with C5b surface association. CFHR1 also competes with complement factor H (CFH) for binding to C3b, and may act as an antagonist...

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Bibliographic Details
Main Authors: Jonathan P Hannan, Jennifer Laskowski, Joshua M Thurman, Gregory S Hageman, V Michael Holers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5096715?pdf=render