New Monoclonal Antibodies for a Selective Detection of Membrane-Associated and Soluble Forms of Carbonic Anhydrase IX in Human Cell Lines and Biological Samples

New Monoclonal Antibodies for a Selective Detection of Membrane-Associated and Soluble Forms of Carbonic Anhydrase IX in Human Cell Lines and Biological Samples

Monoclonal antibodies (MAbs) selectively targeting tumor-associated antigens such as carbonic anhydrase IX (CA IX) can significantly contribute to research, diagnostics, and treatment of CA IX-related cancers. CA IX is overexpressed in numerous hypoxic cancers where it promotes tumor progression. Th...

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Bibliographic Details
Main Authors: Dovile Stravinskiene, Aiste Imbrasaite, Vilma Petrikaite, Daumantas Matulis, Jurgita Matuliene, Aurelija Zvirbliene
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
monoclonal antibodies
human carbonic anhydrase IX
immunoassays
cancer biomarkers
Online Access:https://www.mdpi.com/2218-273X/9/8/304

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