The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas.

The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas.

<label>RATIONALE AND OBJECTIVE</label>Sirtuin 1 (SIRT1) plays an important role in tumorigenesis and is increased in many human tumors. DBC1 is a negative regulator of SIRT1 via promotion of p53-mediated apoptosis. It is necessary to investigate the expression of SIRT1 and DBC1 in laryng...

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Bibliographic Details
Main Authors: Xue-Min Yu, Ying Liu, Tong Jin, Jun Liu, Juan Wang, Chao Ma, Xin-Liang Pan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689713?pdf=render

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