No Evidence for the Involvement of Leiomodin-1 Antibodies in the Pathogenesis of Onchocerciasis-Associated Epilepsy

No Evidence for the Involvement of Leiomodin-1 Antibodies in the Pathogenesis of Onchocerciasis-Associated Epilepsy

Nodding syndrome has been suggested to be triggered by neurotoxic leiomodin-1 auto-antibodies cross-reacting with <i>Onchocerca volvulus</i>. Here, we screened serum and CSF samples of persons with nodding syndrome and other forms of onchocerciasis-associated epilepsy (OAE) and African a...

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Bibliographic Details
Main Authors: An Hotterbeekx, Melissa Krizia Vieri, Melanie Ramberger, Ashraf Jozefzoon-Aghai, Michel Mandro, Floribert Tepage, Alfred Dusabimana, Samir Kumar-Singh, Maarten J. Titulaer, Robert Colebunders
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
onchocerciasis-associated epilepsy
nodding syndrome
leiomodin-1
autoimmune
Online Access:https://www.mdpi.com/2076-0817/10/7/845

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