A conserved behavioral state barrier impedes transitions between anesthetic-induced unconsciousness and wakefulness: evidence for neural inertia.

One major unanswered question in neuroscience is how the brain transitions between conscious and unconscious states. General anesthetics offer a controllable means to study these transitions. Induction of anesthesia is commonly attributed to drug-induced global modulation of neuronal function, while...

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Bibliographic Details
Main Authors: Eliot B Friedman, Yi Sun, Jason T Moore, Hsiao-Tung Hung, Qing Cheng Meng, Priyan Perera, William J Joiner, Steven A Thomas, Roderic G Eckenhoff, Amita Sehgal, Max B Kelz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912772?pdf=render