Lung cancer in patients with tuberculosis

• Main Authors: Vencevičius Vladislavas, Cicėnas Saulius
• Format: Article
• Language: English
• Published: BMC 2007-02-01
• Series: World Journal of Surgical Oncology
• Online Access: http://www.wjso.com/content/5/1/22

<p>Abstract</p> <p>Background</p> <p>Coexistent lung cancer and pulmonary tuberculosis is an urgent problem of thoracic surgery presenting a challenging task for diagnosis and surgical treatment.</p> <p>Materials and methods</p> <p>From 1990 to 2005, 2218 patients with lung cancer underwent surgical treatment in Department of Thoracic Surgery and Oncology, Institute of Oncology, Vilnius University. In 46 (2.1%) patients coexistence of lung cancer and tuberculosis was found. Central lung cancer was diagnosed in 37 (80.4%) and peripheral – in 9 (19.6%) patients. Epidermoid cancer was diagnosed in 24 (52.2%) patients, adenocarcinoma – in 10 (21.7%) and adenoepidermoid carcinoma – in 12 (26.1%) patients. Stage I cancer was diagnosed in 12 (26.1%), stage II – in 11 (23.9%), and stage IIIA – in 23 (50%) patients.</p> <p>Results</p> <p>Pneumonectomy was performed in 18 (39.2%), lobectomy in 10 (21.7%), bilobectomy in 10 (21.7%), segmentectomy in 8 (17.4%) patients. Postoperative surgical complications were observed in 9 (19.5%) patients, non-surgical complications occurred in 19 patients (41.3%). Six patients (13.04%) died. Combined treatment was applied to 23 (50%) patients.</p> <p>Conclusion</p> <p>Coexistence of tuberculosis and lung cancer in thoracic surgery is fairly rare. This combination was diagnosed only in 46 cases (2.1%) out of 2218 operated lung cancer patients. Epidermoid carcinoma and stage IIIA disease was diagnosed in 50% of patients. Postoperative surgical complications occurred in 9 patients (19.5%) with lung cancer and tuberculosis. Six patients (13%) died in postoperative period. Surgery is the method of choice in treatment of combination of tuberculosis and lung cancer. Median survival of these patients was 28 ± 2 months.</p>