K-ras2 Activation and Genome Instability Increase Proliferation and Size of FAP Adenomas

K-ras2 Activation and Genome Instability Increase Proliferation and Size of FAP Adenomas

The possible role of K‐ras2 mutations and aneuploidy toward increase of proliferation and adenoma size in Familial Adenomatous Polyposis (FAP) adenomas is not known. The present study addresses these issues by investigating 147 colorectal adenomas obtained from four FAP patients. The majority of ade...

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Main Authors: Anna Rapallo, Andrea Sciutto, Elio Geido, Roberto Orecchia, Edmondo Infusini, Natalija Pujic, Emanuele S.G. d’Amore, Roberto Monaco, Mauro Risio, Francesco P. Rossini, Walter Giaretti
Format: Article
Language:English
Published: Hindawi Limited 1999-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/1999/257265

Internet

http://dx.doi.org/10.1155/1999/257265

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