Physiological and Clinical Impact of Repeated Inhaled Oxygen Variation on Erythropoietin Levels in Patients After Surgery

Physiological and Clinical Impact of Repeated Inhaled Oxygen Variation on Erythropoietin Levels in Patients After Surgery

The “Normobaric Oxygen Paradox” (NOP) is a physiologic mechanism that induces an increase of endogenous erythropoietin (EPO) production by creating a state of relative hypoxia in subjects previously exposed to hyperoxia, followed by a rapid return to normoxia. Oxygen exposure duration and inspired o...

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Bibliographic Details
Main Authors: Maher Khalife, Mohammed Ben Aziz, Costantino Balestra, Joseph Valsamis, Maurice Sosnowski
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
hematopoiesis
normobaric hyperoxia
normobaric oxygen paradox (NOP)
transfusion alternatives
relative hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.744074/full

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