Improving the estimation of celiac disease sibling risk by non-HLA genes.

Improving the estimation of celiac disease sibling risk by non-HLA genes.

Celiac Disease (CD) is a polygenic trait, and HLA genes explain less than half of the genetic variation. Through large GWAs more than 40 associated non-HLA genes were identified, but they give a small contribution to the heritability of the disease. The aim of this study is to improve the estimate o...

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Bibliographic Details
Main Authors: Valentina Izzo, Michele Pinelli, Nadia Tinto, Maria Valeria Esposito, Arturo Cola, Maria Pia Sperandeo, Francesca Tucci, Sergio Cocozza, Luigi Greco, Lucia Sacchetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210127?pdf=render

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